Sexton T Spatial Genome Organization Methods and Protocols 2022 | 7.75 MB
English | 330 Pages

Title: Spatial Genome Organization: Methods and Protocols (Methods in Molecular Biology Book 2532)
Author: Tom Sexton
Year: 2022

Next Generation Genome Sequencing: Towards Personalized Medicine By
2008 | 280 Pages | ISBN: 3527320903 | PDF | 8 MB
Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.Content: Chapter 1 Sanger DNA Sequencing (pages 1-11): Artem E. Men, Peter Wilson, Kirby Siemering and Susan ForrestChapter 2 Illumina Genome Analyzer II System (pages 13-28): Abizar Lakdawalla and Harper VansteenhouseChapter 3 Applied Biosystems SOLiD™ System: Ligation?Based Sequencing (pages 29-42): Vicki Pandey, Robert C. Nutter and Ellen PredigerChapter 4 The Next?Generation Genome Sequencing: 454/Roche GS FLX (pages 43-56): Lei Du and Michael EgholmChapter 5 Polony Sequencing: History, Technology, and Applications (pages 57-76): Jeremy S. EdwardsChapter 6 Next?Generation Sequence Data Analysis (pages 77-88): Leonard N. BloksbergChapter 7 DNASTAR's Next?Generation Software (pages 89-94): Tim Durfee and Thomas E. SchweiChapter 8 Real?Time DNA Sequencing (pages 95-101): Susan H. HardinChapter 9 Direct Sequencing by TEM of Z?Substituted DNA Molecules (pages 103-116): William K. Thomas and William GloverChapter 10 A Single DNA Molecule Barcoding Method with Applications in DNA Mapping and Molecular HaDescriptionyping (pages 117-132): Ming Xiao and Pui?Yan KwokChapter 11 Optical Sequencing: Acquisition from Mapped Single?Molecule Templates (pages 133-151): Shiguo Zhou, Louise Pape and David C. SchwartzChapter 12 Microchip?Based Sanger Sequencing of DNA (pages 153-163): Ryan E. Forster, Christopher P. Fredlake and Annelise E. BarronChapter 13 Multiplex Sequencing of Paired End Ditags for Transcriptome and Genome Analysis (pages 165-182): Chia?Lin Wei and Yijun RuanChapter 14 Paleogenomics Using the 454 Sequencing Platform (pages 183-199): M. Thomas P. GilbertChapter 15 ChIP?Seq: Mapping of Protein-DNA Interactions (pages 201-215): Anthony Peter Fejes and Steven J. M. JonesChapter 16 MicroRNA Discovery and Expression Profiling using Next?Generation Sequencing (pages 217-228): Eugene Berezikov and Edwin CuppenChapter 17 DeepSAGE: Tag?Based Transcriptome Analysis Beyond Microarrays (pages 229-244): Kare L. Nielsen, Annabeth H. Petersen and Jeppe EmmersenChapter 18 The New Genomics and Personal Genome Information: Ethical Issues (pages 245-254): Jeantine E. Lunshof

The Finger Millet Genome
English | 2022 | ISBN: 3031008677 | 298 Pages | PDF True | 8 MB
This book is the first comprehensive compilation of deliberations on domestication, genetic and genomic resources, breeding, genetic diversity, molecular maps & mapping of important biotic stress as well as nutritional quality traits, genome sequencing, comparative genomics, functional genomics and genetic transformation. The economic, nutritional and health benefits especially antioxidants mediated antiaging effects of finger millet are also discussed. It also presents the input use efficiency, wide adaptation, post-harvest processing and value addition of the crop. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in genetics, pathology, molecular genetics and breeding, genetic engineering, structural and functional genomics and nutritional quality aspects of the crop. This book is also useful to seed and pharmaceutical industries.

English | 2022 | ISBN: 1032301988 | 111 pages | True PDF | 3.04 MB
This remarkable book tells you everything you need to know about vaccines. Having nearly 40 years' experience of the subject, the author covers the history of vaccines, how they work, how research is carried out, their safety, how they are used in society, the inside track on COVID-19 and what the future holds. It is a deeply personal account, with anecdotes involving a cow called Blossom, a hospital in the Caribbean, a crocodile-infested lake in Malawi, an encounter with Russian soldiers in Prague and many others. An A-to-Z section covers every vaccine from Anthrax to Yellow Fever. It will educate, entertain and enlighten the vaccine scientific community and public health practitioners.

English | 2022 | ISBN: 1119671345 | 355 pages | True PDF EPUB | 18.76 MB
GENOME EDITING IN DRUG DISCOVERYA practical guide for researchers and professionals applying genome editing techniques to drug discovery
InGenome Editing in Drug Discovery,a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology's history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues.

My Beautiful Genome: Exposing Our Genetic Future, One Quirk at a Time By Lone Frank
2011 | 328 Pages | ISBN: 1851688331 | EPUB | 1 MB
What if you could predict your future - which political party you will vote for, what kind of person you will marry, which disease will end your life, whether your blue mood will fester into something more troubling, even debilitating. Would you want to know? Taking a uniquely intimate and cheeky approach to the personal genomics revolution, internationally acclaimed science writer Lone Frank swabs up her genetic code to explore who any of us are in the days when a catalogue of your full six billion DNA building blocks is available for $10,000 and the local Walgreens offers genetic screening tests to anyone. She challenges the august Nobel Prize winners and the hyperactive business mavericks who are pushing to map and decipher every fetus's genome within the next decade. She tests the potential to detect diseases early, as well as our capacity to develop chronic anxieties when our DNA is seen as a death sentence. She ponders whether personality, including her own above-average irritability and non-conformity, can really be reduced to biochemistry. And she prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century - a quest made all the more gripping as Frank considers her family's and her own struggles with depression. At turns compellingly candid and irreverently insightful, Frank provides the first truly personal account of the new science of consumer-led genomics - and to what extent our genes determine our destiny. Lone Frank is the author of The Neurotourist: Postcards from the Edge of Brain Science (ISBN 9781851687961). She holds a PhD in neurobiology and was previously a research scientist working in the biotechnology industry in the United States. An award-winning science journalist and TV documentary presenter, she has written for such publicationsn as Scientific American, Science, and Nature Biotechnology and is a frequent speaker at venues including Harvard Medical School, the Library of Congress, the Royal Society, and TED. Praise for The Neurotourist "A fascinating exploration of the most intriguing brain experiments so far." New Scientist "Riveting." Rita Carter, author of Mapping the Mind

Ming Tan, "Chlamydia Biology: From Genome to Disease"
English | ISBN: 1912530287 | 2020 | 492 pages | PDF | 6 MB
Chlamydia is an important bacterial pathogen and a major cause of human and animal disease. Each year, more cases of chlamydial infection are reported to the Centers for Disease Control and Prevention than all other infections combined, illustrating its enormous public health impact. This book provides an up-to-date review of the clinical infections caused by the two main human pathogens C. trachomatis and C. pneumoniae, as well as chapters on veterinary Chlamydia species and Chlamydia-related bacteria. Multiple chapters cover cutting-edge developments in Chlamydia research, from the basic biology of the intracellular chlamydial infection to the host immune response and work towards a Chlamydia vaccine. Also highlighted are recent advances in chlamydial genetics and genomics, which have transformed the field. For the first time in a book, there are chapters on cell division and differentiation and infections and the microbiota, which are two hot areas of research. Each of the nineteen chapters is written by experts, who have made major contributions through their work and come from different research groups to ensure a broad and fresh perspective. This book will be of interest to researchers, microbiologists, cell biologists, infectious disease clinicians, public health professionals and government policy makers. It will be especially useful for newcomers to the field, who will find a current and comprehensive summary of research in one volume.

English | 2022 | ISBN: 3030915069 | 512 pages | True PDF EPUB | 33.21 MB
This book is the first comprehensive compilation of deliberations on elucidation and augmentation of the genome of Brassica juncea, one of the leading oilseed crops of the world, popularly called as brown mustard, Indian mustard, Chinese mustard, or Oriental mustard. It includes discussions on genepools; genetic diversity and its characterization; classical genetic and traditional breeding; basics and application of heteroploidy; techniques and applications of introgressive hybridization; in vitro culture for micro-propagation, somatic mutation, somatic embryogenesis, and somatic hybridization; genetic engineering including genetic transformation and gene silencing; and molecular genetic mapping and mapping of genes and comprehensive delineations on genome sequencing and comparative genomics; resequencing for elucidation of origin and diversity; large-scale genome analysis; plastid genome sequence; transcriptomics; metabolomics; proteomics; evolutionary genomics; role of regulatory genes in development and adaptation and their utilization in trait improvement; precise breeding for yield, quality, and resistance to biotic and abiotic stresses; and prospects of genome editing.

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English | 2022 | ISBN: 3030933938 | 113 pages | pdf, epub | 19.04 MB
This book is the first comprehensive compilation describing the importance of sandalwood in national and international markets, genetic resources, molecular markers, whole genome sequencing, and pathway genes involved in oil biosynthesis, aroma and fragrance. Application of various "omics" approaches in delineating genome architecture and annotation of genes is highlighted. This book comprises 10 chapters covered over 200pages authored by the researchers involved in sandalwood genomics.

The Catharanthus Genome by Chittaranjan Kole
English | EPUB | 2022 | 201 Pages | ISBN : 3030892689 | 30.6 MB
This book is the first comprehensive compilation of deliberations on botany, medicinal importance, genetic diversity, classical genetics and breeding, in vitro biosynthesis, somatic embryogenesis, genetic transformation, molecular mapping, genome sequence, and functional genomics of Catharanthus roseus. Catharanthus is the most important medicinal plant in the world that contains about 130 therapeutic alkaloids out of which vinblastine and vincristine are the two highly used anticancer drugs sold by the pharmaceutically industries.