Free Download The Human Genome (Great Discoveries in Science) by Megan Mitchell
English | April 26th, 2018 | ISBN: 1502619539 | 128 pages | True EPUB | 11.14 MB
The Human Genome explores the science and the history behind the specific sequences in our DNA that make us human. Reaching all the way back to the 1850s when Gregor Mendel used his pea plant experiments to solve the mystery of trait inheritance, this book maps out each theory that laid the groundwork to piece together who we are and why. The Human Genome looks at the important medical advances this knowledge has gained us and the social issues surrounding them.

Free Download Plant Genome Engineering
English | 2023 | ISBN: 1071631306 | 680 Pages | PDF EPUB (True) | 48 MB
This volume provides readers with a collection of the latest protocols used to study plant genome editing and trait engineering. The chapters in this book are organized into five parts: genome engineering systems; machinery design and validation; delivery tools; generation and analysis of engineering materials; and crop genome engineering applications. The chapters cover topics such as methods of applying the popular CRISPR-Cas9 or CRISPR-Cas12 systems for editing genomes in different crop species, the use of small synthetic plastome for potato genome engineering, and the use of CRISPR-Cas9 for algal cell genome engineering. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Free Download The Flax Genome
English | 2023 | ISBN: 3031160606 | 294 Pages | PDF EPUB (True) | 75 MB
The Flax Genome is a comprehensive compilation of most recent studies focused on reference genome, genetic resources and molecular diversity, breeding, QTL mapping, gene editing tools, functional genomics and metabolomics, molecular breeding via genomic selection, and genomic resources. The flax genome reference sequences and the new genome assemblies are presented. A list of flax QTL and candidate genes associated with more than 35 traits, including yield and agronomic, seed quality and fatty acid composition, fibre quality and yield, abiotic stress, and disease resistance traits, are summarized. A QTL- based genomic selection strategy and genome-editing tools are systematically introduced. In addition, huge amounts of flax genomic resources generated in the last decade are summarized.

Free Download Genome: The Autobiography of a Species in 23 Chapters (Audiobook)
English | January 18, 2011 | ASIN: B004JNNTT8 | MP3@32 kbps | 12h 20m | 166.19 MB
Author: Matt Ridley
Narrator: Simon Prebble
The genome's been mapped. But what does it mean?

Genome Editing in Animals (2nd Edition)
English | 2023 | ISBN: 1071630156 | 396 Pages | PDF (True) | 16 MB
This second edition provides new and updated protocols that can be used for generation of knockout animals. Chapters guide the reader through basic protocols for three genome editing technologies, target design tools, and specific protocols for each animal. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Hatada I Genome Editing in Animals Methods and Protocols 2ed 2023 | 15.78 MB
N/A | 396 Pages

Title: GenomeEditinginAnimals
Author: N/A
Year: N/A

Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, "Genome-Based Therapeutics: Targeted Drug Discovery and Development: Workshop Summary"
English | 2012 | pages: 90 | ISBN: 0309260248 | PDF | 5,3 mb
The number of new drug approvals has remained reasonably steady for the past 50 years at around 20 to 30 per year, while at the same time the total spending on health-related research and development has tripled since 1990. There are many suspected causes for this trend, including increases in regulatory barriers, the rising costs of scientific inquiry, a decrease in research and development efficiency, the downstream effects of patient expirations on investment, and the lack of production models that have successfully incorporated new technology. Regardless, this trajectory is not economically sustainable for the businesses involved, and, in response, many companies are turning toward collaborative models of drug development, whether with other industrial firms, academia, or government. Introducing greater efficiency and knowledge into these new models and aligning incentives among participants may help to reverse the trends highlighted above, while producing more effective drugs in the process.

Genome-Based Therapeutics explains that new technologies have the potential to open up avenues of development and to identify new drug targets to pursue. Specifically, improved validation of gene-disease associations through genomics research has the potential to revolutionize drug production and lower development costs. Genetic information has helped developers by increasing their understanding of the mechanisms of disease as well as individual patients' reactions to their medications. There is a need to identify the success factors for the various models that are being developed, whether they are industry-led, academia-led, or collaborations between the two.

Genome-Based Therapeutics summarizes a workshop that was held on March 21, 2012, titled New Paradigms in Drug Discovery: How Genomic Data Are Being Used to Revolutionize the Drug Discovery and Development Process. At this workshop the goal was to examine the general approaches being used to apply successes achieved so far, and the challenges ahead.

The Seabuckthorn Genome
by Prakash C. Sharma
English | 2022 | ISBN: 303111275X | 391 pages | True PDF EPUB | 65.59 MB

The Saffron Genome
by Jyoti Vakhlu, Sheetal Ambardar, Seyed Alireza Salami, Chittaranjan Kole
English | 2022 | ISBN: 3031099990 | 302 pages | True PDF EPUB | 57.38 MB
This book is about Saffron ( Crocus sativus L.) that is the most expensive spice in the world. Though there are other books on saffron but none of them has comprehensive information on saffron genome, transcriptome, proteome, metabolome and microbiome. The book has been divided into five sections and 17 chapters that cover all the areas related to its cultivation, market & economy, genomics, transcriptomics, proteomics, metabolomics, tissue culture, microbiomics, metagenomics etc. In addition a chapter on molecular markers and their use in molecular genetic mapping in saffron that lacks genetic diversity as a sterile plant paves a way for selection of elite varieties based on the epigenetic variability. A section on in-vitro propagation elaborates on the corm production under controlled conditions. In summary this book encompasses most of the information available on this golden spice

English | 2022 | ISBN: 3031055837 | 183 pages | True PDF EPUB | 97.63 MB
This book will expound the latest information on the current state of persimmon genomics and transcriptomics, with a particular focus on the latest findings and analysis in relation to the most important agronomic traits. The genus Diospyros contains about 400 species distributed all continents of the globe. Most of Diospyros species are distributed in the tropical and subtropical regions, while cultivated persimmon or simply kaki ( Diospyros kaki ) originates in East Asia and has been grown in China, Japan and Korea for many years. World production of persimmon has been increasing continuously since 1990s, with China being the most producer. Outside Asia, kaki production has been rapidly increasing in Spain in recent years. Because kaki is mostly hexaploid (2n = 6x =90) and its genome size is quite large with the flow cytometric analysis estimation of about 900 Mb, genetic and molecular studies in persimmon are quite complicated. Diploid close relatives of kaki, D. lotus and D. oleifera have been recently used as model species of kaki. Utilizing these species, molecular basis of several economically molecular basis of important traits such as sexuality and astringency has been studied, giving important information for kaki breeding.