English | 2022 | ISBN: 0367767937| 431 pages | True PDF | 20.59 MB
After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation.

English | 2021 | ISBN: 1032063637 | 475 pages | pdf | 119.48 MB
The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry highlights the necessity for an integrative approach in medicinal chemistry and chemical biology. As medicinal chemistry is not a monolithic science, it is important to emphasize the other various disciplines that are required for successful drug design. This book presents the author's own personal experience in this field and describes the "ups" and "downs" that come with drug discovery. It is an excellent companion text for graduate and postgraduate students who would like further insight into the parameters of drug design, including the challenges that come with the project.

English | 2021 | ISBN: 9814877751 | 789 pages | pdf | 38.65 MB
Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared to conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires many evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles' (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

MP4 | Video: h264, 1280x720 | Audio: AAC, 48 KHz, 2 Ch
Genre: eLearning | Language: English | Duration: 11 lectures (30 mins) | Size: 317 MB
Essential knowldge from evidence point of view

The DopThe Real History of the Mexican Drug Trade | 2.15 MB
English | 468 Pages

Title: The Dope: The Real History of the Mexican Drug Trade
Author: Benjamin T. Smith
Year: 2021

English | 2021 | ISBN: 1032041730 | 321 pages | pdf | 24.85 MB
Drug Discovery with Privileged Building Blocks traces back PharmaBlock's founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book.
Each chapter may be read and studied without learning the previous chapters. This book will be a good starting point for novice medicinal chemists, and veteran medicinal chemists will find it useful as well.

Quantitative Decisions in Drug Development
English | 2021 | ISBN: 3030797309 | 354 Pages | PDF EPUB | 30 MB
This book focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug. It takes a holistic approach towards drug development by incorporating explicitly knowledge learned from the earlier part of the development and available historical information into decisions at later stages. In addition, the book shares lessons learned from several select examples published in the literature since the publication of the first edition.

Nursing2021 Drug Handbook
English | 2021 | ISBN: 1975138392 | 194 Pages | EPUB | 3.33 MB
More than 8,200 clinical updates -new dosages and indications, Black Box warnings, adverse reactions, nursing considerations, clinical alerts, and patient teaching information

Albert P. Li, "Transporters and Drug-Metabolizing Enzymes in Drug Toxicity"
English | ISBN: 1119170842 | 2021 | 528 pages | PDF | 8 MB
This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity, along with methods to investigate their role on adverse drug reactions.

Bret Berner, "Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics"
English | ISBN: 1119772737 | 2021 | 464 pages | EPUB, PDF | 10 MB + 7 MB
Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts in the field