Free Download Human iPSC-derived Disease Models for Drug Discovery
English | 2023 | ISBN: 3031423488 | 574 Pages | PDF EPUB (True) | 31 MB
Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.

Free Download Human Microbiome in Health, Disease, and Therapy
English | 2023 | ISBN: 9819951135 | 597 Pages | PDF EPUB (True) | 33 MB
This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.

Free Download Brooke Goldner M.D., "Goodbye Autoimmune Disease: How to Prevent and Reverse Chronic Illness and Inflammatory Symptoms Using Supermarket Foods"
English | 2019 | pages: 253 | ISBN: 1729813909 | EPUB | 3,3 mb
In this sequel to Goodbye Lupus, Dr. Brooke Goldner details how she used her hyper-nourishment protocol to help real people all over the world get their lives back from Lupus, Rheumatoid Arthritis, Sjogren's, Scleroderma, Psoriasis, Hashimotos and many more using supermarket foods. She also dives deeply into the mindset needed to change your diet and take back your health including motivation, overcoming self-sabotage, and embracing health and happiness. This book will get you inspired, prepared, and excited to take back your health the way they did. You will learn: * The 6 Steps to Reversing Disease with Supermarket Foods * How to get relief from pain, brain fog, inflammation, and chronic fatigue so you can feel alive again *How your mindset can keep you sick and also be the key to reversing your autoimmune disease *How to turn getting healthy into a habit *How to stop sabotaging yourself on your disease-reversal nutrition plan *How to conquer health anxiety *Learn from numerous case studies of real people who changed their lifestyle and their diet and were able to heal from Lupus, Scleroderma, Rheumatoid Arthritis, Sjogren's, Mixed Connective Tissue Disease, Nephritis, Hypothyroid, Psoriasis, Multiple Sclerosis, and Chronic Pain. And much, much more.

Free Download Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations
English | 2022 | ISBN: 1284183831 | 887 Pages | PDF (True) | 82 MB
Updated to keep pace with the many changes in the field, Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations, Eleventh Edition provides readers with a clear, well-illustrated explanation of the structural and functional changes associated with disease, the clinical manifestations of disease, and how to determine treatment. It reflects current information on the pathenogenesis of infectious disease and how changes in the genome are expressed as disease. The first chapters of the text discuss general concepts and diseases affecting the body as a whole. Later chapters consider the various organ systems and their diseases. The Eleventh Edition includes new content on COVID-19, Zika virus, brain eating amoebas, plus mini podcasts to address difficult concepts such as cancer and the use of microscope slides. Each new print copy includes Navigate Advantage Access that unlocks a comprehensive and interactive eBook with animations, student practice activi

Free Download Crohn's Disease and Ulcerative Colitis: A Complete Guide for Patients
English | 2023 | ISBN: 3031454065 | 157 Pages | PDF EPUB (True) | 4 MB
This book provides a complete overview of Crohn's disease and ulcerative colitis for the general reader. Written for patients, their friends and families, and any medical or non-medical persons who wish to learn more about Inflammatory Bowel Disease (IBD), it explains the science in clear, accessible language.

Free Download Satish Mittal, "Coronary Heart Disease in Clinical Practice"
English | 2005 | pages: 238 | ISBN: 1852339365 | PDF | 1,2 mb
Concise and thorough reference book

Free Download Biology of Infectious Disease: From Molecules to Ecosystems
English | 2023 | ISBN: 3031389409 | 315 Pages | PDF EPUB (True) | 144 MB
This textbook provides a broad introduction to the biological processes underlying infectious diseases in a range of hosts and pathogens. The text covers topics at all levels of biological organization, from the molecular and cellular level, organismal level, and population and ecosystem level, and goes well beyond infectious diseases of humans. The details of how microbes interact with their hosts are unique for each interaction, but emphasis is on the common principles of host-pathogen interactions that result in disease.

Free Download Advances in Plant Disease Management: Volume I: Fundamental and Basic Research
English | 2024 | ISBN: 1032516062 | 347 Pages | PDF (True) | 18 MB
Advances in Plant Disease Management: Volume I: Fundamental and Basic Research is an invaluable compilation for researchers/students/stakeholders/policymakers in agriculture. The book aims to offer the latest understanding of fundamental and basic research fronts toward managing crop plants diseases. After clearly explaining the updated knowledge on the host immune system, and pathogen's interplay with the host as unraveled through genomics, bioinformatics, and molecular studies, this book equips readers with the knowledge to confidently account for them during the formulation of management strategies for major crop plant diseases.

Free Download Plant Pathology and Disease Management: Principles and Practices
by S. Parthasarathy
English | 2023 | ISBN: 1032711949 | 456 pages | True PDF | 49.57 MB

Free Download Hansen's Disease: A Complete Clinical Guide
English | 2023 | ISBN: 3031308921 | 323 Pages | PDF (True) | 19 MB
Hansen's disease (leprosy) is endemic in more than 100 countries worldwide, with over 200,000 new diagnoses each year and more than 4 million people living with some form of HD-related impairment. The World Health Organization's 'Global Leprosy Strategy' timeline for Hansen's disease elimination indicates that it will be encountered in clinical practice in endemic countries for at least another decade. Increasing north-to-south migration, global travel and overseas medical work mean that physicians in non-endemic countries will also encounter patients with Hansen's disease, which can affect people for many years before diagnosis and after treatment. For busy clinicians, it represents a challenge, in terms of disease learning and updating knowledge and skills.