This book critically reflects on the latest scientific knowledge regarding the increasing instability of the Earth System caused by human activities during the Anthropocene and the Great Acceleration. It focuses on the global and European challenges regarding climate, resources, bio-integrity, and environment. The authors assess the obstacles to overcoming these challenges and examine the risks posed by path dependencies, lock-ins, and trade-offs between global and regional goals. They also drill down into the complexities of the European Green Deal, specifically the similarities and differences between the scientific analyses and recommendations from the European Environment Agency and the content of the Deal. Finally, the book looks at the Just Transition put forward by the European Green Deal. The authors discuss this in a context of global and European ecological and socioecological challenges and put the question of equality, recognition, and democratization at the center.