Double Helix History: Genetics and the Past
English | 2023 | ISBN: 0367512351 | 223 Pages | PDF (True) | 5 MB
Double Helix History examines the interface between genetics and history in order to investigate the plausibility of 'new' knowledge derived from scientific methods and to reflect upon what it might mean for the practice of history.

Schizophrenia and Genetics: The End of an Illusion by Jay Joseph
English | April 13, 2017 | ISBN: 1483598187 | True EPUB | 185 pages | 1.4 MB
We are approaching a period of crisis and reevaluation in the behavioral genetics and psychiatric genetics fields, as attempts to discover "genes for behavior" have, with possible rare exceptions, been unsuccessful. Schizophrenia is the most investigated psychiatric disorder, yet although there have been many claims of gene "association," decades of molecular genetic studies have failed to produce a single causative gene. In an official 2013 press release, the American Psychiatric Association admitted that psychiatry and its psychiatric genetics subfield are "still waiting" for the identification of "biological and genetic markers" for psychiatric disorders. Although some gene discovery claims have appeared since then, psychiatry continues to "wait."

María Isidoro García, "Molecular Genetics of Asthma"
English | 2016 | pages: 293 | ISBN: 1493936506 | PDF | 6,0 mb

Molecular Genetics of Inflammatory Bowel Disease By Xinjun Cindy Zhu M.D., Richard P. MacDermott M.D. (auth.), Mauro D'Amato, John D Rioux (eds.)
2013 | 343 Pages | ISBN: 1461482550 | PDF | 6 MB
Research in Crohn's disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others).

Principles of Cancer Genetics
English | 2022 | ISBN: 3030993868 | 753 Pages | PDF EPUB (True) | 68 MB
Particular attention is devoted to the origins of cancer and the application of evolutionary theory to explain how mutant cell populations tend to expand and spread. Focused on the genes and signaling pathways involved in the most common tumors, Principles of Cancer Genetics is a highly readable account that will be of interest to anyone who would like to attain a basic understanding of cancer biology. Students who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff will find this book to be a useful starting point toward mastery of this complex but fascinating topic. This updated edition delves into the critical interactions between growing tumors and the immune system, and introduces the concepts of T cell activation, immunoediting and immune evasion. Novel strategies for cancer diagnosis and prognosis, including new roles for next-generation sequencing and liquid biopsies, as well as established and emerging therapeutic modalities are now described in detail.

Sean B. Carroll, Jennifer K. Grenier, Scott D. Weatherbee, "From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design"
English | 2004 | ISBN: 1405119500 | PDF | pages: 270 | 59.5 mb
In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development.

English | ASIN: B09NX36SSP | 2022 | 5 hours and 14 minutes | MP3 | M4B | 143 MB
An urgent plea for a broader understanding and awareness of the unconsidered dangers of new genetic technologies. Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices. Engaging and accessible, this clarion call for responsible and informed stewardship of the human genome provides an overview of what we do and do not know about human genetics and looks at some of the complex, yet largely unexplored, issues we must be most careful about as we move into an era of increasing numbers of parents exercising direct control over the genomes of their children.

Coronavirus Replication and Reverse Genetics by Luis Enjuanes
English | PDF | 2005 | 260 Pages | ISBN : 3540214941 | 3.3 MB
Coronaviruses are the RNA viruses with the largest genome known to date (27 to 32 kb). Members of this virus family affect most domestic animal species, causing important socio-economical losses, and also infect humans.

English | 2022 | ISBN: 978-9811660047 | 334 pages | pdf, epub | 36.25 MB
This book provides insight into the use of molecular and genomic techniques to the study of populations of critically important species at various geographical scales. It delves into a wide range of issues relevant to biodiversity conservation, such as population differentiation, landscape genomics, ecological interactions, phylogenetics, phylogeography, metagenomics, molecular methods, and data processing. The current rate of biodiversity loss is unprecedented and valuable genetic resources are being lost at an alarmingly rate. Effective strategies to conserve these genetic resources are essential to maintain healthy ecosystems with inter-dependent species. The book is an invaluable resource for training undergraduate and graduate students, postdoctoral fellows, and for young researchers. This book is particularly useful for the policy makers and academics who want to learn about important concepts in population and conservation genetics and genomics.

English | 2021 | ISBN: 1119293901 | 883 pages | True PDF EPUB | 81.11 MB
A comprehensive volume providing broad and detailed coverage of marine mussels