English | 2021 | ISBN: 1138058599 | 264 pages | True PDF | 6.3 MB
Statistical Thinking in Clinical Trialscombines a relatively small number of key statistical principles and several instructive clinical trials to gently guide the reader through the statistical thinking needed in clinical trials. Randomization is the cornerstone of clinical trials and randomization-based inference is the cornerstone of this book. Read this book to learn the elegance and simplicity of re-randomization tests as the basis for statistical inference (the analyze as you randomize principle) and see how re-randomization tests can save a trial that required an unplanned, mid-course design change.

English | 2021 | ISBN: 1138048984 | 241 pages | True PDF | 4.02 MB
Confidence Intervals for Discrete Data in Clinical Research is designed as a toolbox for biomedical researchers. Analysis of discrete data is one of the most used yet vexing areas in clinical research. The array of methodologies available in the literature to address the inferential questions for binomial and multinomial data can be a double-edged sword. On the one hand, these methods open a rich avenue of exploration of data; on the other, the wide-ranging and competing methodologies potentially lead to conflicting inferences, adding to researchers' confusion and frustration and also leading to reporting bias. This book addresses the problems that many practitioners experience in choosing and implementing fit for purpose data analysis methods to answer critical inferential questions for binomial and count data.

English | 2021 | ISBN: 1119603161 | 301 pages | True PDF EPUB | 15.04 MB
Clinical Dilemmas in Diabetesanswers the clinical questions commonly encountered when diagnosing, treating, and managing patients with diabetes and its associated complications. Designed to support informed, evidence-based care, this authoritative clinical guide includes contributions from leading endocrinologists and diabetes researchers that discuss a diverse range of recent developments. Concise and focused chapters cover prediabetes, diabetes diagnosis, initial evaluation and management, disease complications, and cardiovascular disease and risk factors.

English | 2021 | ISBN: 1647240387 | 322 pages | True PDF | 90.62 MB
Anatomical knowledge is vital not only for the safe and successful execution of surgical procedures, but also as the basis for accurate diagnosis and treatment planning. This in-depth anatomical text is designed with the practicing implantologist in mind, and it has been revitalized to have the utmost relevance to the clinical reality of oral implantology today. Impeccable full-page illustrations demonstrate a detailed view of each anatomical area, and clinical photos, radiographs, CBCT scans, and cadaver specimens provide a complete picture of what the clinician can expect to encounter. As in the previous edition, the aim of this book has been to present the necessary anatomical material in a readable and interesting form, and every effort has been made to sequence the information in a logical manner. This book is a must-have for any implant surgeon.

Clinical Psychology - A Very Short Introduction []
epub | 655.83 KB | English | Isbn:‎ 0198753896 | Author: Susan Llewelyn, Katie Aafjes-van Doorn | Year: 2017

English | 2021 | ISBN: 0367565293 | 449 pages | True PDF | 4.73 MB
This book provides instruction for health professionals wanting to gain knowledge about the clinical aspects of cannabis medicine. How to use cannabis with real patients, not just theoretically, its pitfalls and challenges, as well as rewards, is a vastly under-covered topic. Now that some form of medical cannabis is approved in almost all US states, health care providers and patientsNeed to Knowhow to achieve maximum benefits by best use of this versatile herbal medicine.

English | 2021 | ISBN: 1536192961 , 978-1536192964 | 324 pages | True PDF | 8.2 MB
The world is experiencing an unprecedented challenge due to coronavirus disease (COVID-19) pandemic. In December 2019, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei province of China. It rapidly spread, resulting in an outbreak of COVID-19. Although the majority of the infected individuals exhibit mild to moderate respiratory illness and recover without requiring special treatment, older people and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer may rapidly progress to acute respiratory distress syndrome, septic shock, coagulation disorders, multi-organ failure, and death. The course of COVID-19 is usually mild in children. However, in rare cases, children can be severely affected, and clinical manifestations may differ from adults. Some children present the multisystem inflammatory syndrome that is similar to incomplete Kawasaki disease or toxic shock syndrome. There is no specific treatment and vaccine for COVID-19. Due to the high infectivity rate of COVID-19, the unexpected and rapid influx of large numbers of patients, especially patients who need intensive care, have caused great pressure on the health care systems worldwide. The worldwide spread of COVID-19 caused fear, anxiety, depression, panic attacks, and a general decrease in overall wellbeing in the population. Healthcare professionals who occupy the front line during pandemics are at increased risk concerning their physical and mental health. The outbreak of COVID-19 negatively affected all aspects of life including education, trade, and tourism. Our knowledge of this novel virus is limited. However, many ongoing clinical trials are evaluating potential treatments and vaccines. A better understanding of the pathogenesis of COVID-19 will provide important insight into its management and reduce the mortality rate. Based on the latest global scientific data and clinical experiences of the authors, this book gives the readers an overview of COVID-19 pathogenesis and transmission routes, current diagnostic and treatment strategies, the clinical course of the disease in children and elderly patients, the genetic background of differences in the incidence of new SARS-CoV-2 infection, the impact of the COVID-19 pandemic on patients with chronic diseases such as diabetes, cancer, cardiovascular diseases, chronic respiratory diseases, antioxidant therapy to limit tissue damage, molecular approaches in COVID-19 treatment, and vaccine studies.

English | 2020 | ISBN: 1119290880 | 423 pages | True PDF EPUB | 70.51 MB
Maintaining the original popular format enjoyed by so many readers, this Second Edition features comprehensive updates to all 66 cases to include the latest diagnostic and treatment techniques. Each chapter also includes brand-new cases, for a total of 13 entirely new cases. The most current references to the literature, best practices, and evidence based clinical guidelines, plus new and updated self‐assessment questions with detailed answers and explanations, have been added to all the cases.

English | 2021 | ISBN: 1119054583 | 123 pages | True PDF EPUB | 102.53 MB
Applied Anatomy for Clinical Procedures at a Glanceis a concise resource combining high-quality images and step-by-step instructions to provide expert guidance on the major core training pathways in medicine, surgery and anaesthesia. Written by an experienced team of Foundation Training programme directors and clinical skills examiners, this unique revision and learning guide aligns with training pathways rather than anatomical area to support Foundation doctors and core trainees master these vital clinical procedures.

English | 2021 | ISBN: 0198841809 | 301 pages | pdf, epub | 21.14 MB
Apathy is characterized by loss of motivation, decreased initiative, and emotional blunting. It is highly prevalent in neurological, and psychiatric disorders like Alzheimer's disease, traumatic brain injury, schizophrenia, Parkinson's disease, Huntington's disease, cerebrovascular disorders, and mild behavioural impairment. It has negative outcomes including impairments in activities of daily living, caregiver burden, and higher rates of institutionalization and