Free Download The Calabar Bean and its Alkaloids: From Magic, via Miracle, to Memory
English | 2023 | ISBN: 9402411909 | 762 Pages | PDF EPUB (True) | 17 MB
Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a "lead compound") have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial.

A. Douglas Kinghorn, "Ancistrocladus Naphthylisoquinoline Alkaloids "
English | ISBN: 3031104560 | 2023 | 346 pages | PDF | 13 MB
This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented.

John S Glasby Auth Encyclopedia Of The Alkaloids Volume 3 Springer Us 1977 | 8.03 MB
N/A | 524 Pages

Title: PreserVision AREDS 2 Eye Vitamin & Mineral Supplement, Contains Lutein, Vitamin C, Zeaxanthin, Zinc & Vitamin E, 120 Softgels (Packaging May Vary)
Author: N/A
Year: 2010